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OSI Pharmaceuticals Announces Acceptance Of Tarceva Supplemental New Drug Application For Review By The U.S. Food And Drug Administration

OSI Pharmaceuticals, Inc. (NASDAQ: OSIP) announced that the U.S. Food and Drug Administration (FDA) has accepted for filing and review the supplemental New Drug Application (sNDA) for the use of Tarceva® (erlotinib) as a first-line maintenance treatment for patients with advanced non-small cell lung (continued...)

Nicotine's Double Role In Lung Cancer

A lung cancer treatment that inhibits nicotine receptors was shown to double survival time in mice, according to Italian researchers. The results of the early phase animal model study were reported in the June 15 issue of the American Journal of Respiratory and Critical Care Medicine. Changes in (continued...)

Defeating nicotine's double role in lung cancer

(American Thoracic Society) A lung cancer treatment that inhibits nicotine receptors was shown to double survival time in mice, according to Italian researchers. (continued...)

Maintenance Treatment With Avastin And Tarceva Aids Lung Cancer

BASEL -- Roche announced today that the Phase III ATLAS study showed patients with advanced non-small cell lung cancer (NSCLC) who received Avastin(R) (bevacizumab) and Tarceva(R) (erlotinib) as combined first-line maintenance treatment had a 39 percent improvement in the time they lived without the (continued...)

New Treatment Approach Gives Patients With Incurable Lung Cancer More Time Without Disease Progression Compared To Placebo

Results from a Phase III study presented at the American Society for Clinical Oncology (ASCO) Annual Meeting in Orlando, Florida today show that patients with advanced non-small cell lung cancer (NSCLC) who received erlotinib (Tarceva®) as first-line maintenance treatment benefited from a significant (continued...)

Bayer And Onyx Initiate Phase III Trial Of Nexavar(R) In Non-small Cell Lung Cancer

Bayer HealthCare AG and Onyx Pharmaceuticals, Inc. today announced that the companies have begun enrolling patients in an international Phase III trial to evaluate Nexavar® (sorafenib) tablets in patients with non-squamous non-small cell lung cancer (NSCLC) who have failed two or three previous (continued...)

Prophylactic cranial irradiation prevents early lung cancer metastases to the brain

A national Radiation Therapy Oncology Group (RTOG) study led by a Medical College of Wisconsin Cancer Center physician at Froedtert Hospital in Milwaukee has found that a course of radiation therapy to the brain after treatment for locally advanced non-small cell lung cancer reduced the risk of metastases (continued...)

Alimta(R) (pemetrexed For Injection) Receives Positive Opinion From CHMP As Maintenance Therapy For Nonsquamous Non-Small Cell Lung Cancer

Eli Lilly and Company (NYSE: LLY) announced that the European Medicines Agency's (EMEA) Committee for Medicinal Products for Human Use (CHMP) has issued a positive opinion for the use of ALIMTA® (pemetrexed for injection) as monotherapy for the maintenance treatment of locally advanced or metastatic (continued...)

Brain irradiation in lung cancer

(Medical College of Wisconsin) A national Radiation Therapy Oncology Group study led by a Medical College of Wisconsin Cancer Center physician at Froedtert Hospital in Milwaukee has found that a course of radiation therapy to the brain after treatment for locally advanced non-small cell lung cancer (continued...)

Lung tumor promotion by curcumin

Curcumin exhibits anti-inflammatory and antitumor activity and is being tested in clinical trials as a chemopreventive agent for colon cancer. Curcumin's chemopreventive activity was tested in a transgenic mouse model of lung cancer that expresses the human Ki-ras^G12C allele in (continued...)

lung-tumors.info - Lung cancer tumors

Latest news and articles about Lung cancer. Up-to-date information about the Symptoms of Lung Cancer, lung tumors, causes and possible treatments. In order to read the article, please click on more... below the article. For more topics click on the left hand menu

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Poisons Under Your Sink: Hidden Dangers of Cleaning Products

The American Association of Poison Control Centers (AAPCC) has recorded many exposures to household cleaning substances that were serious enough to require treatment in a health care facility. Incredibly, according to the AAPCC the largest number of occurrences of poisoning in 1993 were due to cleaning products - drain cleaners, toilet bowl cleaners, bleach, soaps and detergents.

One Million poisonings in Canada each year are due to household cleaner ingestion. Some are fatal. Thousands of children and adults are permanently disfigured or injured through contact with chemicals in the home each year.

Our pets are also at risk. Animals that don't have access to clean, fresh water are more likely to drink out of puddles, gutters, toilet bowls, or any old container left sitting around with a liquid in it. Even though my cats always have access to clean water in a bowl, they seem to prefer the toilet, the sink, the bathtub, or even a basin with cleaning solution in it.

Here is an alphabetical list of some of the most hazardous cleansers found around the house:

AIR FRESHENERS: interfere with your ability to smell by releasing nerve-deadening agents or coating nasal passages with an oil film, usually methoxychlor, a pesticide that accumulates in fat cells. Known toxic chemicals found in an air freshener are formaldehyde, a highly toxic, known carcinogen, and phenol. When phenol touches your skin it can cause it to swell, burn, peel, and break out in hives.

AMMONIA: is a very volatile chemical and is very damaging to your eyes, (continued...)

New Hope to Prevent Breast Cancer: What Every Woman Needs to Know

In March, 2005, a major nutritional breakthrough in the fight against breast cancer was announced by U.S. scientists. This new information is absolutely critical for every woman looking for a natural way to reduce breast cancer risk.

Researchers at Cornell University found that extracts from ordinary apples "effectively inhibited mammary cancer growth" in laboratory animals. The study concluded that "consumption of apples may be an effective strategy for cancer prevention."

The study, "Apples Prevent Mammary Tumors in Rats," was published in the Journal of Agricultural and Food Chemistry.

Phytochemicals from apples- known as polyphenols- have previously shown effectiveness against colon, lung, liver and stomach cancer, among others. But this is the first published study showing that apple polyphenols may be even more effective against breast cancer tumors.

Beyond Breast Cancer Prevention?

In the recent study, treatment with apple extracts prevented new tumor formation by up to 44% in animals given the highest amount.

But the most startling finding- and by far the most significant- is this: after 6 months of treatment, the number of existing tumors was reduced by 61%.

This remarkable finding indicates that adequate doses of apple polyphenols may go beyond prevention, and actually reduce existing mammary tumors.

What Can This Mean for You?

The researchers at Cornell believe that apple polyphenols may prevent breast cancer in humans. If this were the only study available, (continued...)

Asthma and Your Household Environment

At first reading, there isn't much extremely shocking in this report. But with a little research, in my opinion it becomes alarming.

This information comes from the Asthma Society of Canada:

"Doctors define asthma as a 'chronic inflammatory disease of the airways' . It is one of the most prevalent chronic conditions affecting Canadians. Asthma can be diagnosed at any age, but often starts in childhood. Its prevalence in Canada has been increasing over the last 20 years and it is estimated that currently over 3 million Canadians have asthma.

"The three strongest risk factors for developing asthma are family history, exposure in infancy to high levels of antigens such as house dust mites, and exposure to tobacco smoke and/or chemical irritants.

"We're all pretty familiar with allergic triggers of asthmatic symptoms, such as mould, animal dander, pollen, dust mites, etc., but perhaps less familiar with non-allergic triggers such as certain drugs, chemicals, fumes and odours, respiratory viral infections, certain weather conditions, strenuous physical exercise, tobacco smoke, and air pollution.

"Urbanization appears to be correlated with an increase in asthma. The nature of the risk is unclear because studies have not taken into account indoor allergens although these have been identified as significant risk factors.

"Experts are struggling to understand why prevalence rates world-wide are, on average, rising by 50% every decade."

Alarming? Yes. Why?

First of all, the report was updated (continued...)

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