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Women Under-Represented In Cancer Research

Women are under-represented in clinical cancer research published in high-impact journals.

Women (continued...)

UNC scientists identify growth factor as possible cancer drug target
(University of North Carolina School of Medicine) Scientists at the UNC Lineberger Comprehensive Cancer Center report finding a new angiogenesis protein, SFRP2, found in the blood vessels of numerous tumor sites, including breast prostate, lung, pancreas, ovarian, colon, kidney tumors and angiosarcomas. (continued...)


New Drug Hope For Advanced Melanoma
Early results of a trial found that a new drug that targets a genetic mutation found in over half of melanoma cases and some other cancers caused tumors to shrink and patients to live around 6 months longer without their disease getting worse, including those whose cancer had spread to the liver, (continued...)


Lung tumor promotion by curcumin

Curcumin exhibits anti-inflammatory and antitumor activity and is being tested in clinical trials as a chemopreventive agent for colon cancer. Curcumin's chemopreventive activity was tested in a transgenic mouse model of lung cancer that expresses the human Ki-rasG12C allele in (continued...)

Wonder Cancer Drug Might Not Be Effective In Early Stages
A "wonder" drug that fights breast, lung and colon cancer by cutting off blood supply to tumors doesn't seem to pack the same punch in colon cancer caught early, according to research from Allegheny General Hospital presented Saturday at a national cancer conference in Florida. Avastin, made by pharmaceutical (continued...)


Doctors in New Hampshire Now Treating Cancer with Non-Invasive Image-Guided Radiosurgery Using Novalis Tx(TM) Technology
A 71-year old man with inoperable lung cancer is able to receive stereotactic body radiotherapy (SBRT) treatment DOVER, N.H., May 26 /PRNewswire-FirstCall/ -- Surgeons told Donald Bickford, 71, that due to the weakened condition of his lungs, ordinary surgery was not an option for removing his lung (continued...)


QIAGEN Launches Novel Product Enabling Non-Invasive Prenatal Diagnostics And Cancer Detection
QIAGEN announced the launch of a novel product for extraction of free circulating fragments of tumor- and fetal-derived nucleic acids as well as viral nucleic acids in human blood. Scientists consider these DNA and RNA fragments to have great potential for the highly sensitive and non-invasive diagnosis (continued...)


AlphaVax Announces Full Enrollment In Phase I/II Study Of Active Immunotherapy In Patients With Advanced Or Metastatic Cancer
RESEARCH TRIANGLE PARK, N.C. -- AlphaVax announced today the completion of enrollment in a Phase I/II CEA cancer immunotherapy study being conducted by the Duke University Comprehensive Cancer Center, Durham, NC. This Phase I/II study is an open-label, dose-escalation study to evaluate the safety and (continued...)


Preclinical Data Presented On ARIAD's Investigational MTOR Inhibitor, Deforolimus, In Lung Cancer And Other Solid Tumor Models
ARIAD Pharmaceuticals, Inc. (NASDAQ: ARIA) announced the results of preclinical studies in support of the ongoing clinical evaluation of its oral investigational mTOR inhibitor, deforolimus, in patients with non-small cell lung cancer and certain other solid tumors. These findings, which are being presented (continued...)


Human lung tumors can eliminate Vitamin D
Human lung tumors have the ability to eliminate Vitamin D, a hormone with anti-cancer activity, a new study from the University of Pittsburgh Cancer Institute (UPCI) suggests. (continued...)



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New Hope to Prevent Breast Cancer: What Every Woman Needs to Know

In March, 2005, a major nutritional breakthrough in the fight against breast cancer was announced by U.S. scientists. This new information is absolutely critical for every woman looking for a natural way to reduce breast cancer risk.

Researchers at Cornell University found that extracts from ordinary apples "effectively inhibited mammary cancer growth" in laboratory animals. The study concluded that "consumption of apples may be an effective strategy for cancer prevention."

The study, "Apples Prevent Mammary Tumors in Rats," was published in the Journal of Agricultural and Food Chemistry.

Phytochemicals from apples- known as polyphenols- have previously shown effectiveness against colon, lung, liver and stomach cancer, among others. But this is the first published study showing that apple polyphenols may be even more effective against breast cancer tumors.

Beyond Breast Cancer Prevention?

In the recent study, treatment with apple extracts prevented new tumor formation by up to 44% in animals given the highest amount.

But the most startling finding- and by far the most significant- is this: after 6 months of treatment, the number of existing tumors was reduced by 61%.

This remarkable finding indicates that adequate doses of apple polyphenols may go beyond prevention, and actually reduce existing mammary tumors.

What Can This Mean for You?

The researchers at Cornell believe that apple polyphenols may prevent breast cancer in humans. If this were the only study available, it might be too early to recommend increased doses of apple phytochemicals.

However, there are multiple studies in different types of cancer, showing that apple polyphenols are anti-proliferative, anti-mutagenic, and highly antioxidant. Consistent results have been obtained in studies on skin cancer, lung cancer, and six other types of human cancer cells.

Now, a new study from Cornell shows that apple polyphenols are also anti-metastatic- they seem to prevent cancers from spreading. This is a crucial finding for those at risk for breast cancer, as well as survivors of the disease.

Can I Just Eat More Apples?

In nearly all the available studies, the highest benefit from apple polyphenols comes with the highest intake. The Cornell scientists said the highest benefit was seen in rats eating the "human equivalent" of six apples a day.

There is no question that phytochemicals in apples are good for you. And one way to get more of them is to substantially increase the number of apples in your diet. But there's a problem...

Aside from the difficulty and expense of eating that many apples (42 apples a week), there is another important health issue- pesticides. Apples are one of the "dirtiest" foods in the U.S. when it comes to pesticides.

A Perfect Solution?

If you or someone you love is at risk for breast cancer, you need to know the answers to these three questions:

1. How many different pesticides are lurking in your apples?

2. Does washing the fruit take care of the problem? (This one may shock you.)

3. How can you get these apple phytochemicals with zero risk of pesticides?

Get the answers by clicking the link at the end of this article now...



David L. Kern is a researcher and publisher of New Health & Longevity, a newsletter devoted to the latest advances in medical nutritional science. Get the full story on this new health discovery now at title="http://www.applepoly.com/preventbreastcancer" target="_blank">www.applepoly.com/preventbreastcancer

 

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